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Schedule

This schedule is tentative and subject to change. It was last updated July 30. All times listed are Eastern Standard Time (EST). Sessions will be held in Strong Hall 101 unless otherwise indicated.

Monday

09:30–12:30

Registrations/In-parallel Tutorial Sessions
Attendees should register for one of the below workshops.

  • Workshop 1, Strong Hall 101: Analyzing and designing metabolic networks with CellNetAnalyzer – Steffen Klamt, Max Planck Institute, Magdeburg, Germany
  • Workshop 2, Strong Hall 103 Working with Metabolic Kinetic Models: Deployment and Analysis – Herbert Sauro, University of Washington, Washington, United States
  • Workshop 3, Strong Hall 104: Metabolic Modeling in the DOE Systems Biology Knowledgebase (KBase) – Christopher Henry, Argonne National Laboratory, Illinois, United States
  • 13:00–13:10

    Introduction
    Conference chair: Cong T. Trinh

  • 13:00–13:05: Conference Chair: Cong T. Trinh, University of Tennessee, Knoxville, Tennessee, United States
  • 13:05–13:10: Conference organizer: Logistics
  • 13:10–13:55

    Keynote Lecture
    Session chairs: Cong T. Trinh and Oliver Ebenhoeh

    Bringing to bear retrosynthesis tools and enzyme engineering for pathway synthesis – Costas Maranas, Pennsylvania State University, Pennsylvania, United States

    13:55–14:00

    Coffee Break

    14:00–15:30

    Applications in Systems/Synthetic Biology/Metabolic Engineering (1)
    Session chairs: Steven Abel and HerbertSauro

  • 14:00–14:20: Identification of Metabolic Pairs Allow a Reliable and Quantitative Analysis of the Finger Sweat Metabolome – Jurgen Zanghellini, University of Vienna, Austria
  • 14:20–14:40: Metabolic Modeling of Cellular Senescence through Multi-Omics Integration – Marian Breuer, Maastricht University, Netherlands
  • 14:40–15:00: Metabolic complementarity applied to the screening of microbiota and the identification of key species – Clemence Frioux, Inria Bordeaux Sud-Ouest, France
  • 15:00–15:30: Using Machine Learning to Characterize Metabolic Pathway Activities – Soha Hassoun, Tufts University, Massachusetts, United States
  • 15:30–15:35

    Coffee Break

    15:35–17:30

    Poster Session 1

    Block 1

    18:30–20:00

    Reception/Dinner at the Hilton [in person only]

    Tuesday

    07:30–08:30

    Registration/Opening

    08:30–10:15

    Fundamentals of Network Structure and Metabolism (1)
    Session chairs: Herbert Sauro and Stefan Schuster

  • 08:30–09:00: Principles of metabolome conservation in mammals – Balázs Papp, Biological Research Center ELKH, Hungary
  • 09:00–09:20: GC-MS-based 13C Metabolic Flux Analysis in Pseudomonads and related species – Michael Kohlstedt, Institute of Systems Biotechnology, Saarland University, Germany
  • 09:20–09:40: Stoichiometric Modeling of String Chemistries – Devlin Moyer, Boston University, United States
  • 09:40–10:00: Modeling Lignin Biosynthesis using Proteomics and Isotopic Labeling Data in Brachpodium Distachyon – Jaime Barros-Rios, University of North Texas, United States
  • 10:15–10:45

    Coffee Break/Networking

    10:45–12:30

    Applications in Systems/Synthetic Biology/Metabolic Engineering (2)
    Session chairs: Ross Carlson and Zita Soons

  • 10:45–11:15: Data driven advanced metabolic modeling of diurnal growth in the model green alga Chlamydomonas reinhardtii – Nanette Boyle, Colorado School of Mines, Colorado, United States
  • 11:15–11:35: Metabolic Network Modeling of Degrader-Cheater Interactions in a Chitin-Decomposing Model Soil Community – Aimee Kessell, University of Nebraska-Lincoln, Nebraska, United States
  • 11:35–11:55: Flux balance network expansion predicts stage-specific human peri-implantation embryo metabolism – Andisheh Dadashi, University of New Mexico, United States
  • 11:55–12:00: Dynamic flux balance analysis reveals the distribution of biochemical subtypes in CAM photosynthesis – Antonio Rigueiro-Masejo, Heinrich Heine University Duesseldorf, Germany
  • 12:00–12:05: Metabolic profiling of cultured erythroblasts for the large scale production of red blood cells – Joan S. Gallego Murillo, Delft University, Netherlands
  • 12:05–12:10: Predicting the Effect of Carbon Substrate on Bioplastic Production in Rhodopseudomonas palustris – Adil Alsiyabi, University of Nebraska-Lincoln, Nebraska, United States
  • 12:10–12:15: Metabolism of Campylobacter jejuni: an integrated in silico and in vitro study – Dipali Singh, Quadram Institute, United Kingdom
  • 12:30–13:30

    Lunch/Networking

    12:30–13:30

    Committee Meeting

    13:30–14:30

    Fundamentals of Network Structure and Metabolism (2)
    Session chairs: Herbert Sauro and Stefan Schuster

  • 13:30–13:50: Thermodynamics of Evolving Metabolic Reaction Networks – Friedrich Srienc, University of Minnesota-Twin Cities, Minnesota, United States
  • 13:50–14:10: Linear energy converter inspired metabolic analysis couples rate and yield in metabolic models – St. Elmo Wilken, Heinrich-Heine-Universität, Düsseldorf, Germany
  • 14:10–14:30: What Is a Stoichiometric Matrix? – Ronan Fleming, Leiden University & National University of Ireland, Galway, Ireland
  • 14:30–15:00

    Coffee Break/Networking

    15:00–17:30

    Poster Session 2

    Block 2

    18:30–20:00

    Group Dinner at Barley’s Taproom and Pizzeria [in person only]

    Wednesday

    07:30–08:30

    Registration/Opening

    08:30–10:15

    Modular and Biosystems Design (1)
    Session chairs: Oliver Ebenhoeh and Cong T. Trinh

  • 08:30–09:00: New Conceptual and Algorithmic Developments Extending the Framework of Minimal Cut Sets for Metabolic Network Design – Steffen Klamt, Max Planck Institute, Magdeburg, Germany
  • 09:00–09:25: In Vivo Thermodynamic Analysis Of Metabolic Networks – Daniel Amador-Noguez, University of Wisconsin-Madison, Wisconsin, United States
  • 09:25–09:50: Modular Design Principles In Biological Systems: Theory, Computation, And Experimental Validation – Cong T. Trinh, University of Tennessee, Knoxville, Tennessee, United States
  • 09:50–10:10: Stress-induced cross-feeding of internal metabolites provides a dynamic mechanism of microbial cooperation – Kapil Amarnath, University of California at San Diego, California, United States
  • 10:15–10:45

    Coffee Break/Networking

    10:45–12:30

    Advances in Methods, Algorithms, and Tools Development (1)
    Session chairs: Sabine Peres and Hyun-Seob Song

  • 10:45–11:05: Metabolic Pathway Analysis in presence of biological constraints – Phillippe Dague, Université Paris-Saclay, France
  • 11:05–11:25: ModelSeed Release 2: High Throughput Genome-Scale Metabolic Model Reconstruction and Analysis – Jose Faria, Argonne National Laboratory, Illinois, United States
  • 11:25–11:45: Pickaxe, JN1224min, & the MINE: Unearthing Enzyme Promiscuity for New Applications – Keith Tyo, Northwestern University, Illinois, United States
  • 11:45–12:05: Integrated Knowledge Mining, Genome-Scale Modeling, and Machine Learning for Predicting Yarrowia lipolytica Bioproduction – YinJie Tang, Washington University in St. Louis, Missouri, United States
  • 12:05–12:10: ModelSEEDpy: A python library for automated model reconstruction and analysis – Filipe Liu, Argonne National Laboratory, Illinois, United States
  • 12:10–12:15: Systematizing the different notions of growth-coupled strain design and a single framework for their computation – Phillipp Schneider, Max Planck Institute, Magdeburg, Germany
  • 12:30–13:00

    Lunch box [in person only]

    12:30–14:30

    Virtual Networking

    13:00–20:00

    Trip to Smoky Mountains [in person only]

    Thursday

    07:30–08:30

    Registration/Opening

    08:30–10:15

    Resource Allocation and Metabolism (1)
    Session chairs: Egils Stalidzans and Ross Carlson

  • 08:30–09:00: Towards Resource Allocation Models for Multicellular Organisms – Anne Goelzer, Université Paris-Saclay, France
  • 09:00–09:20: Efficient Dry Mass Utilization May Explain Bacterial Growth Laws That Relate Catalyst Concentrations With Growth Rate – Martin Lercher, Heinrich Heine University Düsseldorf, Germany
  • 09:20–09:40: Integrative Modeling of Enzymatic Coordination of Saccharification And Fermentation In Consolidated Bioprocessing of Cellulose – Firnaaz Ahamed, University of Nebraska-Lincoln, Nebraska, United States
  • 09:40–10:00: Growth Mechanics: The Economy, Control, and Optimality of Self-Replication – Hugo Dourado, Heinrich Heine University, Germany
  • 10:00–10:20: Functional analysis of metabolism quantifies protein costs for the synthesis of biomass components in E. coli – Matteo Mori, University of California at San Diego, California, United States
  • 10:30–11:00

    Coffee Break/Networking

    11:00–11:40

    Keynote Lecture
    Session chairs: Egils Stalidzans and Ross Carlson

    Dynamic Allocation of Proteomic Resources by E. coli in Rich and Minimal Media – Terence Hwa, University of California at San Diego, United States

    11:40–12:30

    Resource Allocation and Metabolism (2)
    Session chairs: Egils Stalidzans and Ross Carlson

  • 11:40–12:00: Pseudomonas aeruginosa Reverse Diauxie Is a Multidimensional, Optimized, Resource Utilization Strategy – Ross Carlson, Montana State University, Montana, United States
  • 12:00–12:20: Comparing Glutamine and Glucose as Fuels of Cancer and Yeast Cells: A Linear Optimization Model – Stefan Schuster, University of Jena, Germany
  • 12:20–12:25: Proteome efficiency of metabolic pathways in Escherichia coli – Xiao-Pan Hu, Heinrich Heine University Duesseldorf, Germany
  • 12:30–13:30

    Lunch/Networking

    13:30–15:00

    Advances in Methods, Algorithms, and Tools Development (2)
    Session chairs: Sabine Peres and Hyun-Seob Song

  • 13:30–13:50: EFMlrs: Massive Parallel and Scalable Enumeration of Elementary Flux Modes – Bianca Buchner, University of Vienna, Austria
  • 13:50–14:10: Applications of Answer Set Programming to the analysis of constraint-based models – Maxime Mahout, Université Paris Saclay, France
  • 14:10–14:30: Introducing New Approaches to Gapfilling and Dynamic Flux Balance Analysis for Genome-Scale Models – Rajib Saha, University of Nebraska-Lincoln, Nebraska, United States
  • 14:30–15:00: Advances in Metabolic Modeling Tools in KBase and ModelSEED Enable Integration of Multiomics Data for Pathway Discovery – Chris Henry, Argonne National Laboratory, Illinois, United States
  • 15:00–15:30

    Coffee Break/Networking

    15:30–17:00

    Advances in Methods, Algorithms, and Tools Development (3)
    Session chairs: Sabine Peres and Hyun-Seob Song

  • 15:30–15:50: ASTHERISC: A method to design microbial communities with maximal thermodynamic driving force for the production of chemicals – Pavlos Stephanos Bekiaris, Max Planck Institute of Magdeburg, Germany
  • 15:50–16:10: Integration Of Metabolic, Ecological, And Kinetic Models To Predict The Dynamics In Context-Dependent Microbial Interactions – Hyun-Seob Song, University of Nebraska-Lincoln, Nebraska, United States
  • 16:10–16:40: A Metabolic Approach To Microbial Community Robustness – William Harcombe, University of Minnesota Twin Cities, Minnesota, United States
  • 18:30–21:00

    Reception/Dinner at Calhoun’s on the River [in person only]

    Friday

    07:30–08:30

    Registration/Opening

    08:30–10:20

    Applications in Systems/Synthetic Biology/Metabolic Engineering (3)
    Session chairs: Zita Soons and Isabel Rocha

  • 08:30–09:00: Whole-body metabolic modelling provides novel insight into host-microbiome crosstalk – Ines Thiele, National University of Ireland, Galway, Ireland
  • 09:00–09:20: Determination of metformin transport parameters between plasma and red blood cells of humans in different scale models – Egils Stalidzans, Latvian Biomedical Research and Study Centre, Riga, Latvia
  • 09:20–09:40: Improving Quantitative Genome-Scale Metabolic Modeling of CHO – Diana Széliová, Austrian Centre of Industrial Biotechnology, Vienna, Austria
  • 09:40–10:00: Modelling of glycogen metabolism and glycogen-related disorders – Yvan Rousset, Heinrich Heine University, Germany
  • 10:00–10:20: The Role of RDCVFL in a Mathematical Model of Photoreceptor Interactions – Erika Camacho, Arizona State University, Arizona, United States
  • 10:20–10:45

    Coffee Break/Networking

    10:45–12:15

    Applications in Systems/Synthetic Biology/Metabolic Engineering (4)
    Session chairs: Oliver Ebenhoeh and Cong T. Trinh

  • 10:45–11:15: Macromolecular crowding regulates spatial organization and gene expression in cell-sized vesicles – Steve Abel, University of Tennessee, Knoxville, Tennessee, United States
  • 11:15–11:35: Is the cytosolic density of a prokaryotic cell optimized for metabolic efficiency? – Tin Yau Pang, Heinrich Heine University Duesseldorf, Germany
  • 11:35–11:55: An Improved Kinetic Model to Explain the Physiological Response of Escherichia coli Under High ATP Demand – Giulia Slaviero, Max Planck Institute, Magdeburg, Germany
  • 11:55–12:15: Dissecting the Metabolic Reprogramming of Maize Root under Nitrogren Limiting Stress Condition – Niaz Chowdhury, University of Nebraska-Lincoln, Nebraska, United States
  • 12:15–12:45

    Poster Awards/MPA2023 Venue/Closing Remarks

    12:45–14:00

    Lunch at the Hilton [in person only]